Answer 1: The most important difference between plasma and serum has to do clotting. Furthermore, plasma is the liquid that is found remaining when the prevention of clotting happens and after adding an anticoagulant. In contrast, serum is the liquid that is found remaining after the blood clotting has taken place. Serum sickness. Serum sickness is a reaction that is similar to an allergy. The immune system reacts to medicines that contain proteins used to treat immune conditions. It can also react to antiserum, the liquid part of blood that contains antibodies given to a person to help protect them against germs or poisonous substances. In whole blood prediluted with distilled water the glucose concentration appeared to be 13% higher than in whole blood prediluted with saline. In plasma, predilution with distilled water or saline did not result in different glucose values. Plasma glucose is significantly higher than whole blood glucose independent of the method of pretreatment How does serum differ from plasma? Serum is the term for fluid plasma with the fibrinogen (clotting factors) removed. It is the clear, pale yellow fluid left when The following activities can boost a person’s levels of HDL cholesterol: using oils with fewer trans fats, such as those from olives, sunflowers, canola, and corn. eating more whole fruits and The biochemical profile of whole blood, serum and plasma is a complex composition of over one thousand small molecules representing multiple biochemical families. In this study, we compared the levels of each compound detected in five different sample types as well as the relative ranges of these biochemicals . Both aspects are important for TjwuAy.